Polysine microscope slides have a special coating that enhances tissue adhesion by creating a permanent positive charge on the slide surface. This allows them to attract and bind tissue sections electrostatically, ensuring samples remain securely attached even under typical laboratory conditions. They are versatile and compatible with automated staining systems, making them ideal for various applications, including immunocytochemical and molecular hybridization assays. Overall, polysine slides improve staining quality, maintain sample integrity, and enhance diagnostic accuracy and research findings.